What is considered a very high CA 125 level?
Generally speaking, the normal range of CA-125 is considered to be 0-35 units/mL, while a level above 35 units/mL is considered to be a high CA-125 level.
How high is CA 125 ovarian cancer?
Cancer antigen 125 (CA 125) is the only tumor marker recommended for clinical use in the diagnosis and management of ovarian cancer. The reference range of CA 125 is 0-35 units/mL (0-35 kU/L).
What level of CA 125 indicates endometriosis?
The mean serum CA-125 level of women with endometriosis was 49.93±4.30 U/mL (range, 2-191 U/mL) in this study. Amara and colleagues found that CA-125 serum levels were higher in endometriosis patients when compared to control group during both periods of menstrual cycle (13).
What cancers does CA 125 detect?
Cancer antigen 125 (CA125) is a protein found on most ovarian cancer cells that is secreted into the blood stream and can be measured….The CA125 blood levels can be increased in ovarian cancer and other cancers including:
- uterine.
- fallopian tube.
- pancreatic.
- breast.
- colorectal.
- lung.
- stomach.
What is a high tumor marker number?
Normal range: < 2.5 ng/ml. Normal range may vary somewhat depending on the brand of assay used. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease.
How quickly can CA 125 rise?
The average time from serum CA125 increase to detection of a recurrent lesion by physical or imaging examination was 122 days. The correlation coefficient of serum CA125 level increase and tumor recurrence time was −0.674.
Can stress cause CA125 to rise?
The most popular current theories suggest that CA 125 is synthesized by mesothelial cells in response to stress, which can be either mechanical stress caused by fluid overload, or inflammatory stress instigated by the release of mediators such as TNFα and interleukins [5,6].